Multiple choice

What type of recombination vector was generally recommended for HGP?

  1. Plasmid

  2. Cosmid

  3. BAC

  4. YAC

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Bacterial Artificial Chromosomes (BACs) were the primary cloning vectors recommended for the Human Genome Project because they could stably maintain large DNA inserts (100-200 kb), were easier to work with than YACs, and provided the stability needed for accurate sequencing of large genomic regions.