Which transport system is used by some tumor cells to pump out drugs?
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PTS system
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Permeases
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Peptones
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Siderophores
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ABC transportes
E
Correct answer
Explanation
Binding protein transport systems or ATP-binding cassette transporters are active in bacteria, archaea and eukaryotes. One of the major problems related with anti-cancer chemotherapy is the resistance against anti cancer drugs. The ATP-binding cassette transporters are a family of transporter proteins that are responsible for drug resistance and a low bioavailability of drugs by pumping a variety of drugs out of cells at the expense of ATP hydrolysis.