Multiple choice

Biphasic reaction in Vandenbergh test is seen in which of following conditions?

  1. Viral hepatitis

  2. Spherocytosis

  3. Carcinoma of head of the pancreas

  4. Stones in the bile ducts

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A Correct answer
Explanation

A biphasic reaction in the Vandenbergh test indicates both hepatocellular damage and partial obstruction. Viral hepatitis causes hepatocellular injury with some degree of cholestasis, resulting in this mixed pattern. Pure obstruction (stones, pancreatic head carcinoma) gives a purely positive reaction, while pure hemolysis gives a negative reaction.