Multiple choice

Which of the following porphyria is associated with chemicals and drugs and occurs due to defect in the uroporphyrinogen decarboxylase?

  1. Variegate porphyria

  2. Porphyria cutanea tarda

  3. Acute Intermittent porphyria

  4. Erythropoietic protoporphyria

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Porphyria cutanea tarda (PCT) is the most common type of porphyria and is associated with exposure to certain chemicals (alcohol, estrogen, hexachlorobenzene) and drugs. It is caused by decreased activity of uroporphyrinogen decarboxylase, leading to accumulation of uroporphyrin. This enzyme defect causes the characteristic blistering skin lesions and photosensitivity seen in PCT.

Keep practicing — related questions