Multiple choice

What is true about Ferrochelatase?

  1. It is an iron chelating agent.

  2. It releases iron from heme in the degradation of Hb.

  3. It binds iron to sulfide ions and cysteine.

  4. Its activity is inhibited by heavy metals.
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D Correct answer
Explanation

Ferrochelatase is the final enzyme in heme synthesis, inserting ferrous iron into protoporphyrin IX. Heavy metals like lead inhibit ferrochelatase activity, which is why lead poisoning causes anemia. It doesn't chelate iron therapeutically, degrade hemoglobin, or bind to sulfide ions.

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