Multiple choice

Mr. Malhotra is suffering from Fanconi syndrome which is a proximal tubule dysfunction. Which of the following is NOT a characteristic feature of this syndrome?

  1. Glycosuria

  2. Phosphaturia

  3. Metabolic acidosis

  4. Excess bicarbonate reabsorption

  5. Hyperkalemia
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D Correct answer
Explanation

In particular, there can be a failure of reabsorption of sodium in the proximal tubule. This results in excess sodium reaching the collecting ducts where some of it is exchanged for potassium, causing excess potassium loss and a low plasma potassium level. Hence, there is a loss of bicarbonate .

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