Which of the following is/are required for the synthesis of haemoglobin?
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Methaemoglobin
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Bilirubin
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Succinyl CoA and glycine
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Oxyhaemoglobin
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Biliverdin
C
Correct answer
Explanation
These compounds are synthesised in normoblastic stage of developing red blood cells. Two molecules of succinyl CoA and two molecules of glycine combine to form a pyrolle ring. Four pyrolles combine together to form protoporphyrin IX. Protoporphyrin IX combines with iron and polypeptide chain to form haemoglobin chain. Four such haemoglobin chains make up haemoglobin molecule.