Multiple choice Which of the following proteins is localised in the core of eosinophil granule? Eosinophilic cationic protein Mannose binding protein Histamine protein Acid phosphatase D protein Reveal answer Fill a bubble to check yourself B Correct answer Explanation Mannose binding protein is a major basic protein and is localised in the core of the granules. In the pre-immune host, its function appears to be pattern recognition in the first line of defense.