Multiple choice

Which among the following statements does NOT characterise telomerase reverse transcriptase enzyme?

  1. The hTERT gene has become a main focus for gene therapy involving cancer.

  2. Plasmid DNA sequences can be manufactured using the hTERT promoter.

  3. hTERT immortalises various normal cells in culture.

  4. The hTERT gene, located on chromosome 5, consists of 16 exons and 15 introns spanning 35 kb.

  5. Telomere deficiency is associated with cancers and tumor formation.

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Telomere deficiency is often linked to aging, cancers and the conditions dyskeratosis congenita (DKC) and Cri du chat. Meanwhile, over-expression of hTERT is often associated with cancers and tumor formation.