Multiple choice

A young woman of 32 is found to have a largely solid ovarian neoplasm. Tumor markers were obtained and demonstrated a markedly elevated LDH value. The hCG and a-Fetoprotein were negative. Which of the following tumors is the most likely histology for this neoplasm?

  1. Dysgerminomas

  2. Gonadoblastoma

  3. Immature teratomas

  4. Choriocarcinoma

  5. Endodermal sinus tumor
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A Correct answer
Explanation

Dysgerminomas, the most frequent germ cell malignancy, are principally solid. Such tumors are most frequent in women with dysgenetic gonads. Pure ovarian dysgerminomas cause an elevated LDH with normal hCG and a-fetoprotein levels.

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