Multiple choice

During downstream process of penicillin fermentation, phosphoric acid or sulphuric acid is added to the medium to _________.

  1. kill all fungi

  2. lower the pH and convert penicillin to anionic form

  3. produce phosphate or sulphate salt of penicillin

  4. precipitate penicillin
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Lower the pH and convert penicillin to anionic form: the acids lower the pH to 2 or 2.5. This helps to convert penicillin to anionic form and the broth is immediately extracted in a Podbielniak counter current solvent extractor.

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