Headache, diarrhoea and common cold last for some time and affect us severely for that short period. But they do not leave any of the effects like weakness. Thus, these are acute diseases.
On the contrary, tuberculosis is chronic because it affects us for a long time and also makes the body weak, even after the infection is cured. It is caused due to bacteria and in this disease, the lungs and the respiratory system are affected. In this, mucus begins to collect in lungs, gradually leading to inefficient gaseous exchange, frequent cough and even bleeding in the throat at later stages. Hence, option (4) is the correct answer.