Multiple choice

Colchicine is employed to diploid a haploid cell as it

  1. inhibits karyokinesis

  2. inhibits formation of mitotic spindle

  3. allows replication of DNA twice in one cell cycle

  4. inhibits formation of centromere
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B Correct answer
Explanation

Colchicine, a drug, which inhibits spindle fibre formation during mitosis and halts cell division at metaphase. This often will result in a doubling of the chromosome number since colchicine typically inhibits cytokinesis, but not karyokinesis. The doubled chromosomes will fuse within a single nucleus, thus diploidising the haploid cell.

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