Multiple choice

A heavy chain is the large polypeptide sub-unit of a protein complex. The first immunoglobulin heavy chain class to be manifested on the surface of a newly produced B-cell in the body is

  1. IgA

  2. IgD

  3. IgE

  4. IgG

  5. IgM

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

IgM is the first immunoglobulin class to be expressed on the surface of the developing B-cells, shortly followed by IgD. Early mature B-cells co-express IgM and IgD antibodies of identical antigen specificity.