Multiple choice

NK cells play a major role in the host-rejection of both tumours and virally infected cells. Which among the following does not characterise Natural Killer (NK) cells of the human body?

  1. Respond to interferon

  2. Contain perforin

  3. Kill only by damaging the target cell outer membrane

  4. Contain tumour necrosis factor (TNF)

  5. Contain serine proteases

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Perforin inserts into the target cell membrane, thereby facilitating entry of TNF and granzymes into the target cell.