Multiple choice Eukaryotic genes do not function properly when cloned into bacterial cell because of high pH present in bacterial cell inability to excise introns and destruction by bacterial restriction enzymes inappropriate insertion of genes both 1 and 2 Reveal answer Fill a bubble to check yourself B Correct answer Explanation Eukaryotic genes do not function properly when cloned into bacterial cell, because of the inability of the bacterial genes to excise introns. Eukaryotic enzymes are often responsible for the destruction of the bacterial restriction enzymes as well.