The series follows the pattern: each term is the previous term multiplied by 2, then minus 1. 5×2-1=9, 9×2-1=17, 17×2-1=33, 33×2-1=65. But wait, the given series is 5, 9, ?, 29, 45. Let's check: 5 to 9 is +4, 9 to 17 is +8, 17 to 29 is +12, 29 to 45 is +16. The differences increase by 4 each time (4, 8, 12, 16). The missing term is 17.