Multiple choice technology mainframe ISC stands for _____? 1) Intra System Communication 2) Inter System Communication 3) Infra System Communication 4) Both 1 and 2 5) Neither 1 nor 3 Reveal answer Fill a bubble to check yourself B,E Correct answer Explanation ISC stands for Inter System Communication. This is a mechanism for communication between different systems or subsystems. Option E (Neither 1 nor 3) is also correct because ISC is not Intra System Communication or Infra System Communication.