They grew up in __________ house in Mexico City.
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a little comfortable
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a comfortable, little
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a little, comfortable
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a comfortable little
To solve this question, the user needs to have knowledge of English grammar rules, particularly the correct order of adjectives.
In this sentence, two adjectives are used to describe the house - "comfortable" and "little". The correct order of adjectives in English is: opinion, size, age, shape, color, origin, material, purpose.
The option that follows this order is:
D. a comfortable little
Option A is incorrect because it is in the wrong order.
Option B is incorrect because it reverses the order of the adjectives.
Option C is incorrect because it also reverses the order of the adjectives.
Therefore, the answer is: D. a comfortable little.
In English, adjective order typically places opinion/quality adjectives ("comfortable") before size adjectives ("little") when both precede a noun, and no comma is used between short adjectives placed this way, giving "a comfortable little house." The other orderings or added commas don't follow standard English adjective-ordering conventions.